The current version of Artemis doesn't support USB dumps (and the version that does dumps to a USB flash drive, not across a male to male prolific). The 'branch' that allowed that was created by Jimmi, and I'll add it to the new Artemis Downloads section...hopefully tonight.
Yes, it would be feasible to perform a series of dumps, take detailed notes about the states of the game during each dump, and then take your flash drive back to a PC and perform comparisons between the dumps. However, you'd still lack a simple method of testing codes. I'll see if I have something that will perform sequential comparisons like that...I believe I do, somewhere.
More importantly, at least minimal progress has been made in forcing screen printing (forcing graphics to display during gameplay), which would allow us to halt the game using normal methods already employed by Artemis, call up a simplistic GUI on the screen, and perform comparisons on the PS2 itself. This will be about three times slower than the ethernet solution (PS2 USB is 1.1, which is less than 1% of the speed of USB 2.0, the USB transfer rates you're likely accustomed to), but will definitely open up hacking to the masses.
Something of note is Bungholio's ASM searcher...which stores its results in the PS2's RAM somehow...if it were possible to implement such a system in Artemis, comparisons would be increasingly faster each time a search narrows the results, and PS2-side hacking would be much more reasonable.
I may be lazy, but I can...zzzZZZzzzZZZzzzZZZ...